Capsida has received FDA IND clearance to initiate a clinical trial for our first-in-class IV-administered investigational gene therapy for STXBP1 Developmental and Epileptic Encephalopathy
UNLOCKING THE POTENTIAL OF GENE THERAPY FOR ALL
About
Science & Innovation
THE CAPSIDA APPROACH
Capsid Engineering, Cargo Optimization, Translational Biology, Process Development and Good Manufacturing Practices (GMP) Manufacturing, and Clinical Development – All Under One Roof to Develop Better Therapies Faster
Capsida Biotherapeutics is the only fully integrated next-generation genetic medicines company that has created all the capabilities needed to deliver on the promise of genetic medicine.
Capsid Engineering
At Capsida, the scale at which we can engineer and screen capsids is unrivaled. Using our automated screening method, our scientists assess large, diverse engineered capsid libraries in non-human primates to quickly identify optimal capsids for disease targets and their corresponding human receptors.
Discovery and Preclinical
To quickly advance our mission of providing meaningful therapeutic opportunities for patients with unmet medical need, Capsida optimizes cargo and evolves preclinical disease proof-of-concept in parallel with capsid engineering. Our engineered capsids can be optimized to deliver a broad range of cargo modalities.
Manufacturing Operations
At Capsida, we are singularly focused on rapidly getting our high-quality, life-changing therapies to patients who are suffering from debilitating diseases. We have built state-of-the-art cGMP manufacturing capabilities to perform everything in-house. We streamline the entire process, from selecting our therapies for manufacturability through scalable process development. Ultimately, this helps us get therapeutics to patients sooner.
Clinical Development
Capsida’s approach unlocks the potential to treat both rare and common diseases across all ages. First and foremost, we approach patients holistically, working closely with advocacy groups, patients, and caregivers to ensure we are meeting their needs.
Team
Capsida’s founding technology originated in the lab of Caltech’s Viviana Gradinaru, Ph.D., Professor of Neurosciences and Biological Engineering at the Tianqiao and Chrissy Chen Institute of Neuroscience. Founded in 2019, Capsida is financed by Versant Ventures and Westlake Village BioPartners and has entered into strategic collaborations with AbbVie, CRISPR Therapeutics, Prevail Therapeutics, a part of Lilly’s Gene Therapy Division, and Kate Therapeutics (acquired by Novartis).
Our leaders have decades of experience in the biopharmaceutical industry and expertise in AAV biology and biologics manufacturing.
Partnering
“Our partnerships with leading global biopharmaceutical companies are key to Capsida achieving its vision of being able to reach more potential patients in need with our enabling genetic medicines.”
Bethany Mancilla, Chief Business Officer
Our goal is to apply the strength of our targeted genetic medicine platform to develop a new generation of transformative therapies. Since our inception, we have entered into strategic collaborations with AbbVie, CRISPR Therapeutics, Prevail Therapeutics, a part of Lilly’s Gene Therapy Division, and Kate Therapeutics (acquired by Novartis).
Careers
BE PART OF OUR DNA
Capsida is a vibrant company based in the heart of the Greater Los Angeles biotech hub. We’re looking for passionate, dedicated colleagues to join us!