“This isn’t just a platform – it’s about patients. Capsida’s approach unlocks the potential to treat both rare and common diseases across all ages.”

Swati Tole, CMO

Capsida Biotherapeutics is an industry-leading gene therapy platform company creating a new class of targeted, non-invasive gene therapies for patients with debilitating and life-threatening disorders.  We blend innovation with execution in the pursuit to improve patient lives.

Science & Innovation


Capsid Engineering, Cargo Optimization, Translational Biology, Process Development and Manufacturing, and Clinical Development – All Under One Roof

Capsida Biotherapeutics is the only fully integrated next-generation gene therapy platform company. Capsida’s approach unlocks the potential to treat both rare and common diseases across all ages.  We create customized therapies that selectively target specific organ systems and simultaneously limit exposure to non-targeted organs.

Built through a combination of in-house R&D and industry partnerships, our therapeutic approaches – including gene replacement and gene editing – are designed to bring therapies to patients with both monogenic and polygenic diseases.


Capsid Engineering

At Capsida, the scale at which we can engineer and screen capsids is unrivaled. Using our automated, high-throughput biological screening method, our scientists assess large, diverse engineered capsid libraries to quickly identify optimal capsids to target tissues and cells in diseased organs.


Discovery and Preclinical

To quickly advance our mission of providing meaningful therapeutic opportunities for patients with unmet medical need, Capsida optimizes cargo and evolves preclinical disease proof-of-concept in parallel with capsid engineering. Our engineered capsids can be optimized to deliver a broad range of cargos including gene replacement, gene editing, gene silencing and vectorized antibodies, among others.


Manufacturing Operations

At Capsida, we are singularly focused on rapidly getting our high-quality, life-changing therapies to patients who are suffering from debilitating diseases. We have built capabilities to perform everything in-house, eliminating the need for contract development and manufacturing organizations (CDMOs). We streamline the entire process, from selecting our therapies for manufacturability through scalable process development. Ultimately, this helps us get therapeutics to patients sooner.


Clinical Development

Capsida’s approach unlocks the potential to treat both rare and common diseases across all ages. First and foremost, we approach patients holistically, working closely with advocacy groups, patients, and caregivers to ensure we are meeting their needs.



Capsida’s innovation and intellectual property can be broadly applied to all therapeutic areas. We began with a focus on the Central Nervous System (CNS) based on the expertise and passion of our founders and the significant prevalence and unmet need in CNS disorders, and have since expanded into serious eye diseases through our partnership with AbbVie.


Capsida’s founding technology originated in the lab of Caltech’s Viviana Gradinaru, Ph.D., Professor of Neurosciences and Biological Engineering at the Tianqiao and Chrissy Chen Institute of Neuroscience. Founded in 2019, Capsida is financed by Versant Ventures and Westlake Village BioPartners and has entered into a strategic partnership with AbbVie for treating neurodegenerative disease.

Our leaders have decades of experience in the biopharmaceutical industry and expertise in AAV biology and biologics manufacturing.


“We welcome the opportunity to collaborate with innovators who share our determination to develop transformative gene therapies for patients.”

Bethany Mancilla, Chief Business Officer

Capsida’s approach unlocks the potential to treat both rare and common diseases across all ages. Our goal is to apply the strength of our targeted gene therapy platform to develop a new generation of transformative therapies.

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Capsida is a rapidly growing company based in the heart of the Greater Los Angeles biotech hub. We’re looking for passionate, dedicated colleagues to join us!

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News & Events


Capsida Biotherapeutics Announces Promotion of Rob Murphy to Chief Manufacturing and Quality Officer

Promotion reinforces commitment to advancing our wholly owned gene therapy pipeline and strength of in-house manufacturing capabilities THOUSAND OAKS, Calif.,…

Capsida Biotherapeutics to Present at Evercore ISI 2024 Emerging Biotech Conference

THOUSAND OAKS, Calif., February 21, 2024 -- Capsida Biotherapeutics (“Capsida”) today announced that Peter Anastasiou, Chief Executive Officer, will present a…